Cannabigerol (CBG) is one of more than 120 identified cannabinoid compounds found in the cannabis plant. It was first discovered in 1964 as a component of hashish. It was later discovered in that CBGA (cannabigerolic acid) is the first cannabinoid formed in plants–cannabis’ first expression. CBGA is then converted into other cannabinoids, primarily tetrahydrocannabinol (THC) or cannabidiol (CBD), leaving about 1% cannabigerol in the plant.
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CBG is a non-psychoactive cannabinoid. Research into its medical properties is currently ongoing. It has not been as thoroughly studied as THC or CBD, but current research is proving to innate health benefits of CBG.
Effects of Cannabigerol
Cannabigerol is non-intoxicating as it is non-psychoactivce, but it does help to create a synergy by balancing the effects of THC with other cannabinoids.
In general, cannabinoids exert their effects by contacting their own receptors, which are present all over the body. CBG acts on both the CB1 and CB2 cannabinoid receptors, but its effect on both receptors is extremely weak compared to the effect of THC.
Anandamide is a cannabinoid that occurs naturally in the body and helps regulate bodily fuctions like sleep, appetite and memory. CBG affects the body by causing an increase in anandamide levels. Anandamide, just like THC, acts on CB1 and CB2 receptors to produce its effects.
CBG is also known to antagonize the serotonin receptors, meaning it may have a role to play in the treatment of depression.
“Research is ongoing at the University at Buffalo on the efficacy of medical marijuana in the treatment of depression caused by stress. The research is focused on endocannabinoids and has shown that chronic stress may inhibit the production of endocannabinoids by the brain. This according to the study, may lead to depression-like behavior. Exposing the system to cannabinoids may facilitate the restoration of optimal function, thus easing depression symptoms.”
Because CBG is able to ac upon the nervous system without any psychotic effects, the benefits and medical use of CBG are currently of great interest to researchers.
Health Benefits of CBG
CBG research is ongoing, but early results show CBG has the potential to treat a variety of different conditions.